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Dimitrios Mantzilas Appointed as Chief Technology Officer and Site Head for Actithera Oslo

Smita SinghbySmita Singh
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Dimitrios Mantzilas Appointed as Chief Technology Officer and Site Head for Actithera Oslo

Dimitrios Mantzilas Appointed as Chief Technology Officer and Site Head for Actithera Oslo

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Oslo, Norway, November 2025 — Actithera, a pioneering radiopharmaceutical biotechnology company, has announced the appointment of Dimitrios Mantzilas as Chief Technology Officer and Site Head for Actithera Oslo. In this dual leadership role, Dimitrios will oversee global technology strategy, R&D initiatives, and operations at Actithera’s Oslo site, driving innovation in next-generation radioligand therapies (RLTs).

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Before joining Actithera, Dimitrios Mantzilas served as Chief Technology Officer at Precirix, a biotechnology company dedicated to advancing precision radiopharmaceuticals for cancer treatment. Over his four-year tenure, he played a key role in the design and development of targeted radiopharmaceuticals using camelid single-domain antibodies labeled with radiometals, contributing to the company’s clinical and regulatory success.

Prior to that, Dimitrios spent more than seven years at Bayer, where he held multiple leadership roles, including Head of Radiopharmaceutical Development (CPD Oslo) and Head of Technology Development. His work at Bayer was instrumental in advancing radiopharmaceutical R&D programs, technical transfers, and regulatory compliance processes, strengthening the company’s footprint in oncology innovation.

Earlier, Dimitrios served as Director of Technology Development at Algeta ASA, where he led key development programs before the company’s acquisition by Bayer. His career also includes nearly a decade at GE Healthcare, where he held positions such as CMC Coordinator, Technology Transfer Leader, and Senior Research Scientist. During his tenure, he played an essential role in enabling PET clinical trials worldwide, leading GMP manufacturing, regulatory documentation, and analytical chemistry programs.

In addition to his corporate leadership, Dimitrios currently serves on the Board of Directors at TAG1 Inc., a medical radioisotope company focused on radioligand therapy supply, and at Extraction Technologies Norway AS, where he supports the development of groundbreaking electromembrane extraction technologies for blood compound analysis.

About Actithera

Actithera is a next-generation radiopharmaceutical biotechnology company translating medicinal chemistry insights into innovative radioligand therapies (RLTs). Founded in 2021 by Dr. Andreas Goutopoulos with backing from M Ventures and Arkin Bio Ventures II, the company leverages unique molecular design strategies—such as covalent-targeting and an isotope-agnostic approach—to develop differentiated radioligand therapies with expanded therapeutic windows.

Headquartered in Oslo, Norway, with operations in Cambridge, Massachusetts, Actithera is committed to addressing unmet needs in oncology through precision-targeted, high-efficacy RLTs that enhance patient outcomes and redefine cancer care.

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Tags: ActitheraBayerbiotechnologyChief Technology OfficerCTO AppointmentDimitrios MantzilasGE HealthCareHappy Place to Work CertificationHPTWLeadership Appointmentoncology innovationPrecirixRadioligand TherapyradiopharmaceuticalsSite Head
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Matthew Breitfelder is Partner and Global Head of Human Capital at Apollo, where he focuses on attracting extraordinary talent to the firm and creating an innovative, inclusive, high-performance culture that brings out the best in Apollo’s people. Matt leads Apollo’s recruiting, talent management, compensation, succession planning, citizenship, employee relations, development, and culture work. He is also a member of the firm’s Leadership Team. Matt is committed to expanding opportunities across Apollo’s workplace, marketplace, and communities. Prior to joining Apollo, Matt was Chief Talent Officer at BlackRock as well as a member of the Operating Committee. Previously, he held strategy, talent, and innovation roles at Mastercard, PwC, and CEB/Gartner.

Matt holds a BA in Economics from the University of Southern California, an MSc from the London School of Economics, and an MBA from Harvard Business School. He currently serves on the boards of the Lumina Foundation, the Aspen Institute’s Business and Society program, the Milken Institute’s Inclusive Capitalism initiative, and Georgetown University’s initiative on AI, Analytics, and the Future of Work. He is the co-author of numerous Harvard Business School case studies and articles on leadership. Matt has been recognized as a Top Global CHRO multiple times by n2Growth and Stanford Business School.

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